THE STUDY OF ESTABLISHMENT OF AN IN VIVO TUMOR MODEL BY THREE-DIMENSIONAL CELLS CULTURE SYSTEMS METHODS AND EVALUATION OF ANTITUMOR EFFECT OF BIOTIN-CONJUGATED PULLULAN ACETATE NANOPARTICLES

In this study, three-dimensional (3D) hydrogels were used for human NEON BLUE hepatocellular carcinoma (HepG2) cells culture systems in vitro and establishment of an in vivo xenografted tumor model.Based on our previous work on the biotin-conjugated pullulan acetate nanoparticles (Bio-PA NPs) as anticancer drug carriers, we further studied the anti

In view of the high dissolved organic matter and salt content of the Mariculture wastewater in coastal industrial clusters, because that moving bed biofilm reactor (MBBR) normally faces the unbalanced carbon -nitrogen ratio and long Military Airplane flow, MBBR is rarely used for wastewater treatment of mariculture wastewater.Moving bed biofilm rea

We present an animal model used to evaluate the in vivo performance of electrochemical amperometric continuous lactate sensors compared to blood gas instruments.Electrochemical lactate sensors were fabricated, placed into 5 Fr central venous catheters (CVCs), and paired with wireless potentiostat devices.Following in vivo evaluation and calibration

Background Chronic dyspnoea and exercise impairment are common after acute pulmonary embolism (PE) but are not defined and quantified sufficiently to serve as outcomes in clinical trials.The planned project will clinically validate a novel method to determine discrete, clinically meaningful diagnoses after acute PE.The method uses an algorithm enti